Lipophilic statins for dyslipidemia penetrate muscle greater without problems than hydrophilic statins and are associated with a higher occurrence of destructive results.
List of statins for dyslipidemia and lipophilic versus hydrophilic treatments:
Fluvastatin (Lescol)
Lovastatin (Mevacor, Altoprev)
Pravastatin (Pravachol)
Simvastatin (Zocor)
Atorvastatin (Lipitor)
Rosuvastatin (Crestor)
Pitavastatin (Livalo)
Myalgia can be associated with lipophilicity (fat loving) and to excessive dosage, in addition to interaction with other medicinal drugs.
Lipophilic statins penetrate muscle more effortlessly than hydrophilic statins and are related to a higher incidence of destructive results, in particular myopathy, despite the fact that reports of muscle toxicity, including rhabdomyolysis, had been suggested with all statins.
Hydrophilic statins stay out of muscle and brain tissue, which might be fats filled.
